NDLI: Non-invasive monitoring of human cerebral oxygen saturation by near infrared spectroscopy: instrumentation, calibration and application in cardiopulmonary bypass

Content Provider	IEEE Xplore Digital Library
Author	Yichao Teng Haishu Ding Qingcheng Gong
Copyright Year	2005
Description	Author affiliation: Departmen of Biomedical Eng., Tsinghua Univ., Beijing (Yichao Teng; Haishu Ding)
Abstract	Cerebral oxygenation especially regional cerebral oxygen saturation $(rSO_{2})$ needs to be monitored to avoid irreversible damages induced by hypoxia. Based on steady-state spatially resolved spectroscopy (SRS), $rSO_{2}$ was obtained by the NIRS oximeter developed by our group. The oximeter was calibrated by blood gas analyzer using the liquid tissue model made up by our group. The results indicate that the correlation between $rSO_{2}$ and the real oxygen saturation of the model is excellent (R>0.99), and the influences by the background absorption and overlaying tissues are little. The $rSO_{2}$ of 14 patients were monitored during cardiopulmonary bypass (CPB) non-invasively by our oximeter. The results indicate that first, NIRS is almost the only available method to monitor $rSO_{2}$ non-invasively during CPB; second, $rSO_{2}$ is negatively correlated with body temperature and positively with blood perfusion rate, so it reflects the balance between cerebral oxygen supply and consumption; third, the low perfusion rate stage and the rewarming stage are relatively critical because $rSO_{2}$ decreases significantly and may be relatively low
Starting Page	670
Ending Page	673
File Size	359803
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1616502
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Infrared spectra Instruments Calibration Cardiology Blood Patient monitoring Steady-state Spatial resolution Spectroscopy
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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