NDLI: Effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold

Content Provider	IEEE Xplore Digital Library
Author	Yan Bige Yang Yanni Yuan Jiangang
Copyright Year	2005
Description	Author affiliation: Shaanxi Normal Univ., Xi'an (Yan Bige; Yang Yanni; Yuan Jiangang)
Abstract	The study was to investigate thrombolysis in vivo with ultrasound, and to discuss effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold, under different ultrasound intensity and exposure time. The structure of erythrocyte in thrombus was evaluated under light microscope. The relationship between the structure of erythrocyte in thrombus and ultrasound intensity and exposure time was obtained. The results showed that ultrasound eliminated the thrombus. According to the change of the structure of erythrocyte in thrombus and ultrasound intensity and exposure time, the effects of thrombolysis with ultrasound could be divided into three kinds of areas: the A, B, C area. The area A was the safe area, the area B was the relatively safe area, and the area C was the irreversible damage area. The study suggested that ultrasound intensity and exposure time had significant impact on the structure of erythrocyte. Too much ultrasound intensity or too long exposure time could cause erythrocytes irreversible damaged. It could accelerate thrombolysis and shorten the exposure time that the ultrasound intensity was little bit increased. This study of effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold were important for practical applications
Starting Page	443
Ending Page	445
File Size	184100
Page Count	3
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1616441
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ultrasonic imaging Safety Blood Cells (biology) Frequency Acoustic transducers Ultrasonic transducers Microscopy Acceleration Helium safe area ultrasound thrombolysis erythrocyte structure
Content Type	Text
Resource Type	Article

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