NDLI: Integrated Vortex Micropumps and Active Micromixers in Polymer Substrates for Automating Bio-fluidic Manipulation

Content Provider	IEEE Xplore Digital Library
Author	Lam, R.H.W. Miao Lei Zaili Dong Kin Fong Lei Li, W.J.
Copyright Year	2005
Description	Author affiliation: Centre for Micro & Nano Syst., Chinese Univ. of Hong Kong (Lam, R.H.W.)
Abstract	This paper presents a microfluidic mixing module array developed for bio-fluid/chemical delivery and mixing. Vortex micropumps, microchannels and pillared-surface diaphragm (PSD) active micromixers were successfully integrated into a single polymer-based microfluidic chip, consisting of three mixing modules. The pumping characteristics of the vortex micropump were investigated with both analytical and experimental results. Experiments were also conducted to examine the factors affecting the PSD-based mixing. The integrated mixing module further demonstrated the feasibility of chemical mixing and concentration control. An integrated fluidic system was shown successfully to deliver bio-fluid for real-time SPR based detection. A computer-controlled fluid manipulation system is also proposed for the real-time microfluidic operation control. The digitally controllability of the pumping and mixing operations could potentially improve the accuracy and efficiency, and hence, the functionality of the integrated microfluidic system
Starting Page	1297
Ending Page	1300
File Size	420765
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1616664
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Micropumps Polymers Microfluidics Impellers Chemicals Pumps Control systems Automatic control Real time systems Plasmons surface plasmon resonance microfluidic system vortex micropump active micromixer cellular detection
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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