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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Chang Ming Li |
| Copyright Year | 2005 |
| Description | Author affiliation: Sch. of Chem. & Biomed. Eng., Nanyang Technol. Univ. (Chang Ming Li) |
| Abstract | Polypyrrole (PPy) is one of the important conductive polymers that are widely used in energy storage systems, biosensors and electronics. The electrochemical synthesis of PPy has advantages of simple process, mass production and low cost. In this study, polypyrolle were used to reporterlessly detect DNA and proteins. PPy thin films impregnated with probe molecules were deposited on both microelectrode and glassy carbon electrode surface by galvanostatic deposition method. Results demonstrated that PPy coated electrodes can be used for successful detection of DNA hybridization and antibody (Ab)-antigen (Ag) bindings. The experimental results also showed that the detection mechanism is probably due to the change of doping/undoping process of the conductive polymer after the DNA hybridization or antibody/antigen bindings |
| Starting Page | 1925 |
| Ending Page | 1928 |
| File Size | 180548 |
| Page Count | 4 |
| File Format | |
| ISBN | 0780387414 |
| DOI | 10.1109/IEMBS.2005.1616828 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2006-01-17 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | DNA Proteins Biosensors Electrodes Energy storage Mass production Costs Conductive films Polymer films Sputtering |
| Content Type | Text |
| Resource Type | Article |
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