NDLI: Electrospun Blends of Natural and Synthetic Polymers as Scaffolds for Tissue Engineering

Content Provider	IEEE Xplore Digital Library
Author	Mengyan Li Mondrinos, M.J. Xuesi Chen Lelkes, P.I.
Copyright Year	2005
Description	Author affiliation: Sch. of Biomed. Eng., Drexel Univ., Philadelphia, PA (Mengyan Li; Mondrinos, M.J.)
Abstract	Engineering functional three-dimensional (3-D) tissue constructs for the replacement and/or repair of damaged native tissues using cells and scaffolds is one of the ultimate goals of tissue engineering. In this study, non-woven fibrous scaffolds were electrospun from the synthetic biodegradable polymer poly(lactic-co-glycolic acid) (PLGA) and natural proteins, gelatin (denatured collagen) and elastin. In the absence of cross-linking agent, the average PGE fiber diameter increased from 347 plusmn 103 nm to 999 plusmn 123 nm upon wetting as measured by scanning electron microscopy. Rat bone marrow stromal cells (rBMSC) were used paradigmatically to study the 3-D cell culture properties of PGE scaffolds. Consistent with the observed properties of the individual fibers, PGE scaffolds initially swelled in aqueous culture medium, however rBMSC seeded PGE scaffolds contracted to < 50% of original size. Time course histological analysis demonstrated uniform seeding of rBMSC into PGE scaffolds and complete cell penetration into the fibrous architecture over 4 weeks of in vitro culture
Starting Page	5858
Ending Page	5861
File Size	370804
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1615822
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Tissue engineering Biomedical engineering Biological materials Chemistry Polymer gels Protein engineering Bones In vitro Laboratories Physics Tissue Engineering Electrospinning Nanofibrous scaffold PLGA Gelatin Elastin
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Electrospun Scaffolds for Corneal Tissue Engineering: A Review

Gelatin Blends Enhance Performance of Electrospun Polymeric Scaffolds in Comparison to Coating Protocols

Braided and Stacked Electrospun Nanofibrous Scaffolds for Tendon and Ligament Tissue Engineering.

Effects of PLGA nanofibrous scaffolds structure on nerve cell directional proliferation and morphology

Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering

In vitro characterization of nanofibrous PLGA/gelatin/hydroxyapatite composite for bone tissue engineering

Preparation of Electrospun Nanofibrous PLGA / Gelatin for Tissue Engineering

Oxygen-plasma treatment-induced surface engineering of biomimetic polyurethane nanofibrous scaffolds for gelatin-heparin immobilization

3D PCL/Gelatin/Genipin Nanofiber Sponge as Scaffold for Regenerative Medicine

Electrospun Blends of Natural and Synthetic Polymers as Scaffolds for Tissue Engineering

Similar Documents

Electrospun Scaffolds for Corneal Tissue Engineering: A Review

Gelatin Blends Enhance Performance of Electrospun Polymeric Scaffolds in Comparison to Coating Protocols

Braided and Stacked Electrospun Nanofibrous Scaffolds for Tendon and Ligament Tissue Engineering.

Effects of PLGA nanofibrous scaffolds structure on nerve cell directional proliferation and morphology

Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering

In vitro characterization of nanofibrous PLGA/gelatin/hydroxyapatite composite for bone tissue engineering

Preparation of Electrospun Nanofibrous PLGA / Gelatin for Tissue Engineering

Oxygen-plasma treatment-induced surface engineering of biomimetic polyurethane nanofibrous scaffolds for gelatin-heparin immobilization

3D PCL/Gelatin/Genipin Nanofiber Sponge as Scaffold for Regenerative Medicine

Electrospun Blends of Natural and Synthetic Polymers as Scaffolds for Tissue Engineering