NDLI: The Effects of Q-Switched Nd:YAG Laser Irradiation in the Wavelength of 1064nm and 532nm on Guinea Pigs' Skin Tissue

Content Provider	IEEE Xplore Digital Library
Author	Zhongben Chen Minran Tang Zhiguang Wang
Copyright Year	2005
Description	Author affiliation: Dept. of Biomed. Eng., Sun Yat-sen Univ., Guangzhou (Zhongben Chen)
Abstract	To investigate the effect of Q-switched Nd:YAG laser irradiation in the wavelength of 1064 nm and 532 nm on guinea pigs' skin tissue, according to the method and dose which are used clinically to treat pigmentary skin diseases, so as to provide some reference and foundation for the clinical usage of Q-switched Nd:YAG laser. Three different doses of Q-switched Nd:YAG laser in the wavelength of 1064 nm and 532 nm were used respectively for in vitro irradiation on guinea pigs, then the histological change of the skin tissue were observed and analyzed with microscope and image analysis instrument. Each experimental group showed obvious histological changes, and with the increase in doses, the extent of change became larger. The single-pulse energy density of Q-switched Nd:YAG laser plays a main role in the change of the skin tissue; with the same irradiation dose there is no difference in the effects of the two wavelengths (1064 nm and 532 nm) on skin tissue; the green light with the wavelength of 532 nm can be absorbed by epidermal melanin granules and shatter the melanin granules much more effectively than the infrared light with the wavelength of 1064 nm; and in the same wavelength, the larger the dose, the better the shattering effect on melanin
Starting Page	6809
Ending Page	6812
File Size	433622
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1616068
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Skin Laser theory Chemical lasers Neodymium Diseases Laser transitions Image analysis Laser modes Biomedical engineering Sun
Content Type	Text
Resource Type	Article

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