NDLI: Ultrasonic Imaging of Myocardial Vibrations Associated with Coronary Artery Disease

Content Provider	IEEE Xplore Digital Library
Author	Sikdar, S. Beach, K.W. Goldberg, S.L. Zwink, T.R. Baughman, L.I. Kim, Y.
Copyright Year	2005
Description	Author affiliation: Dept. of Electr. Eng., Washington Univ., Seattle, WA (Sikdar, S.)
Abstract	Coronary artery disease (CAD) is a major cause of mortality in the western world. Although progress has been made in recent years for the noninvasive diagnosis of CAD, a widely available, inexpensive and effective diagnostic solution remains elusive. We have developed a novel ultrasound-based technology to detect and analyze the myocardial vibrations associated with diastolic murmurs produced by CAD. Conventional ultrasound imaging systems suppress these vibrations. We have developed algorithms to process the raw ultrasound data and isolate these vibrations and integrated them into a programmable ultrasound system for real-time vibration imaging. In preliminary results from clinical studies of patients with CAD, we have observed localized areas of vibrations in the neighborhood of the stenosed coronary artery. The vibrations are narrowband with frequency >200 Hz, and appear to have harmonic components, thus indicating resonance phenomena potentially with nonlinear mechanisms involved. No such vibrations were observed in normal subjects. Analysis of myocardial vibrations could provide a noninvasive diagnostic test for CAD that overcomes many of the limitations of conventional noninvasive tests. Potentially, this technology could provide a new way of evaluating CAD and cardiac function
Starting Page	1087
Ending Page	1090
File Size	476321
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1616608
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ultrasonic imaging Myocardium Coronary arteriosclerosis Testing Noninvasive treatment Isolation technology Real time systems Arteries Narrowband Frequency ultrasound Coronary artery disease cardiac murmurs myocardial vibrations
Content Type	Text
Resource Type	Article

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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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