NDLI: Characteristics of the fibroplasia and collagen expression in the abdominal wall after implant of the polypropylene mesh and polypropylene/polyglecaprone mesh in rats

Content Provider	Scientific Electronic Library Online (SciELO)
Author	Biondo-Simões, Maria de Lourdes Pessole Morais, Camila Gomes de Tocchio, Anna Flávia Zonato Miranda, Renata Augusta de Moura, Paula Almeida Pamponet Colla, Kelly Robes, Rogério Ribeiro Ioshii, Sérgio Ossamu Tomasich, Flávio Daniel Saavedra
Abstract	ABSTRACT PURPOSE: To compare fibroplasia and the resistance of the abdominal wall when polypropylene meshes and polypropylene/poliglecaprone are used. METHODS: Seventy-seven male Wistar rats were divided into three groups: Control Group (for resistance); Group E (polypropylene mesh); and Group U (polypropylene/poliglecaprone mesh). The animals in Groups E and U had a standard muscular and aponeurotic defect, with integral peritoneum, and correction with the mesh. Measurements were taken 4, 7, 14, 28 and 56 days after surgery. The resistance, and collagen density were studied. RESULTS: Resistance on the 56th day was similar in both meshes. The gain in resistance described an ascending curve for the polypropylene mesh and was irregular in the case of the polypropylene/poliglecaprone. Fibroplasia showed a gain in type I and type III collagen in both groups (p<0.001). Collagen III stabilized in the 14th day and collagen I continued to ascend. CONCLUSIONS: The gain in resistance of the polypropylene mesh is regular and ascending, whereas the polypropylene/poliglecaprone is not regular. The final resistance of both meshes is similar; the collagen density increases over time, and show the same inflammatory potential.
Related Links	http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-86502016000500294&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502016000500294&lng=en&nrm=iso
Starting Page	294
Ending Page	299
Page Count	6
File Format	PDF
ISSN	01028650
DOI	10.1590/S0102-865020160050000001
Journal	Acta Cirurgica Brasileira
Issue Number	5
Volume Number	31
Language	English
Publisher	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Publisher Date	2016-05-01
Access Restriction	Open
Subject Keyword	Surgical Mesh Hernia, Ventral Wound Healing Collagen Rats
Content Type	Text
Resource Type	Article
Subject	Surgery

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