NDLI: Evaluation of the effects of carbon dioxide pneumoperitoneum on abdominal wall wound healing in rats undergoing segmental resection and anastomosis of the left colon

Content Provider	Scientific Electronic Library Online (SciELO)
Author	Morais, Pedro Henrique Alves de Farias, Igor Eduardo Caetano de Durães, Leonardo de Castro Carneiro, Fabiana Pirani Oliveira, Paulo Gonçalves de Sousa, João Batista de
Abstract	PURPOSE: To evaluate the influence of carbon dioxide pneumoperitoneum on abdominal wall wound healing in rats. METHODS: Eighty rats underwent laparotomy, segmental left colon resection, and anastomosis. The animals were divided into three experimental groups and one control group: EI = pneumoperitoneum for 30 minutes before laparotomy (n=20); EII = pneumoperitoneum for 30 minutes after abdominal closure (n=20); EIII = pneumoperitoneum for 30 minutes before laparotomy and 30 minutes after abdominal closure (n=20); C = control group, without pneumoperitoneum (n=20). In each group, 10 animals were killed 7 days and 10 animals 14 days postoperatively. A segment of the abdominal wall was resected and subjected to tensile strength testing. Another segment of abdominal muscle was used for histopathological analysis; the specimens were fixed in formalin and stained with hematoxylin and eosin. RESULTS: There were no differences in histopathology and tensile strength values among animals in the experimental and control groups 7 or 14 days after surgery. CONCLUSION: Under the present experimental conditions, carbon dioxide pneumoperitoneum did not interfere with abdominal wall wound healing.
Related Links	http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-86502012000100011&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000100011&lng=en&nrm=iso
Starting Page	63
Ending Page	70
Page Count	8
File Format	PDF
ISSN	01028650
DOI	10.1590/S0102-86502012000100011
Journal	Acta Cirurgica Brasileira
Issue Number	1
Volume Number	27
Language	English
Publisher	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Publisher Date	2012-01-01
Publisher Institution	UnB Medical School
Publisher Place	Brazil
Access Restriction	Open
Subject Keyword	Abdominal Wall Wound Healing Pneumoperitoneum, Artificial Tensile Strength Rats Parede Abdominal Cicatrização Pneumoperitônio Artificial Resistência à Tração Ratos
Alternative Title	Avaliação dos efeitos do pneumoperitônio com dióxido de carbono na cicatrização da parede abdominal de ratos submetidos à ressecção segmentar e anastomose no cólon esquerdo
Content Type	Text
Resource Type	Article
Subject	Surgery

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