NDLI: Task-based evaluation of motion compensated reconstructed images using 4D channelized Hotelling observer in dual gated SPECT

Content Provider	IEEE Xplore Digital Library
Author	Taek-Soo Lee Tao Feng Frey, E. Tsui, B.M.W.
Copyright Year	2013
Description	Author affiliation: Dept. of Radiol., Johns Hopkins Univ., Baltimore, MD, USA (Taek-Soo Lee; Tao Feng; Frey, E.; Tsui, B.M.W.)
Abstract	We developed a 4D SPECT image reconstruction method with respiratory motion (RM) and cardiac motion (CM) compensation, and evaluated its performance using a previously developed 4D channelized Hotelling observer (CHO) model for the task based evaluation of 4D medical images. A series of 4D XCAT (eXtended CArdiac Torso) phantoms with and without a regional CM abnormality was generated that divided a respiratory cycle into 24 frames and a cardiac cycle into 48 frames for each respiratory phase. Almost noise-free projection data were generated from the 1152 3D XCAT phantoms at each respiratory and cardiac (R&C) gated time frame using the SimSET simulation modeling a typical 99mTc Sestamibi gated myocardial perfusion (GMP) SPECT study. They were scaled and combined to form 6 equal-amplitude respiratory gates and 8 equal-time cardiac gates. Poisson noise was then added before image reconstruction using the 3D OS-EM with or without RM and CM compensation. Using a group-wise B-spline non-rigid image-based registration method, the deformation field (DF) of the RM were estimated and applied to each cardiac phase of the R&C gated SPECT images for RM correction. Then, the RM compensated GMP SPECT images were transformed using the estimated DF of the CM. The 2D reconstructed image slices were extracted and reorganized into a set of cine images and the space-time channels of the 4D CHO were applied to produce the space-time feature vectors to which the receiver operating characteristic (ROC) was applied and areas under the ROC curve (AUC) values calculated. The result demonstrated that the RM and CM compensated images showed drastically reduced noise level without blurring and its AUC values were significantly higher than those without compensation. We conclude that the RM and CM compensation allow significant reduction of image blurring and noise level in dual gated SPECT images resulting in significant improvement in detecting a regional CM abnormality using a 4D CHO model.
Starting Page	1
Ending Page	4
File Size	1190319
Page Count	4
File Format	PDF
e-ISBN	9781479905348
DOI	10.1109/NSSMIC.2013.6829067
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-10-27
Publisher Place	South Korea
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Logic gates Myocardium Single photon emission computed tomography Phantoms Noise Heart SPECT respiratory and cardiac motion dual gating compensation 4D image reconstruction channelized Hotelling observer
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in