NDLI: Time alignment of time of flight positron emission tomography using the background activity of LSO

Content Provider	IEEE Xplore Digital Library
Author	Rothfuss, H. Moor, A. Young, J. Panin, V. Hayden, C.
Copyright Year	2013
Description	Author affiliation: Siemens Mol. Imaging, Knoxville, TN, USA (Rothfuss, H.)
Abstract	Time alignment of a positron emission tomography scanner (PET) is an important calibration as the nature of the data collected in PET is inherently time-correlated. This calibration is a key concern in scanners which employ time-of-flight (TOF) capability to localize events along a particular segment of a line of response. Emission data collected with TOF information requires the time difference measured by the scanner to be tightly coupled to the spatial information such that the true origin of the annihilation event of the radioisotope is colocated in both the time and spatial domains. There are many techniques to time align a PET scanner but all involve an external source. Our research shows that the background radiation of LSO provides an intrinsic source of radiation that can be used to measure and correct the time offsets for detector pixels. The physical distances of the static pixel locations can be compared to the measured time of flight of background events generated by LSO beta decay and cascade gamma traversing the PET field of view. The resulting information can be used to correct for the time offset between a pixel and all other pixels that the originating pixel is in coincidence with. This method can enable system operators to perform continuous time alignment whenever the system is idle, and can reduce personnel radiation exposure by reducing the need to handle sources during the calibration process.
Starting Page	1
Ending Page	3
File Size	251916
Page Count	3
File Format	PDF
e-ISBN	9781479905348
DOI	10.1109/NSSMIC.2013.6829400
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-10-27
Publisher Place	South Korea
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Crystals Positron emission tomography Timing Calibration Histograms Detectors
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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