NDLI: Phase space reconstruction of an experimental model of cardiac field potential in normal and arrhythmic conditions

Content Provider	IEEE Xplore Digital Library
Author	Binbin Xu Jacquir, S. Laurent, G. Bilbault, J.-M. Binczak, S.
Copyright Year	2013
Description	Author affiliation: LE2I Univ. de Bourgogne, Dijon, France (Jacquir, S.; Laurent, G.; Bilbault, J.-M.; Binczak, S.) \|\| Team GeoStat, INRIA Bordeaux Sud-Ouest, Bordeaux, France (Binbin Xu)
Abstract	Cardiac arrhythmias are one of the most important death causes in the world. Compared to the numerical models, the experimental ones provide a more realistic tool to study the mechanisms of cardiac arrhythmias. The in vitro culture of cardiac cells developed on the Multi-Electrodes Array (MEA) constitutes a suitable model in this context. The extracellular field potential (EFP) acquired from the MEA can be used to measure the electrophysiological parameters of action potential. In this article, the stability of this experimental model is investigated using the phase space reconstruction in normal and in arrhythmia conditions. The results show that the embedding dimension of signal EFP changed slightly in both cases (normal conditions and arrhythmia). The parameter time lag τ in the normal conditions is lower than in the arrhythmia. The shape of attractors remains similar but disturbed in case of arrhythmia compared to the normal conditions.
Starting Page	3274
Ending Page	3277
File Size	1568419
Page Count	4
File Format	PDF
ISBN	9781457702167
ISSN	1557170X
DOI	10.1109/EMBC.2013.6610240
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-07-03
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrical stimulation Trajectory Electric potential Electrodes Heart Arrays Spirals
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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