NDLI: Timing and source of the maximum of the transthoracic impedance cardiogram (dZ/dt) in relation to the H-I-J complex of the longitudinal ballistocardiogram under gravity and microgravity conditions

Content Provider	IEEE Xplore Digital Library
Author	Luchitskaya, E. Deliere, Q. Diedrich, A. Pattyn, N. Almorad, A. Beck, L. Gauger, P. Limper, U. Funtova, I. Baevsky, R.M. Migeotte, P.-F. Tank, J.
Copyright Year	2013
Description	Author affiliation: Inst. of Clinical Pharmacology, Hannover Med. Sch., Hannover, Germany (Tank, J.) \|\| Inst. of Biomed. problems, Moscow, Russia (Luchitskaya, E.; Funtova, I.; Baevsky, R.M.) \|\| Sch. of Med., Dept. of Med., Vanderbilt Univ., Nashville, TN, USA (Diedrich, A.) \|\| Vital signs & Performance Res. Unit, R. Mil. Acad., Brussels, Belgium (Deliere, Q.; Pattyn, N.; Almorad, A.; Migeotte, P.-F.) \|\| Inst. of Aerosp. Med., German Aerosp. Center (DLR), Cologne, Germany (Beck, L.; Gauger, P.; Limper, U.)
Abstract	The transthoracic impedance cardiogram (ICG) and the acceleration ballistocardiogram (BCG) measured close to the center of mass of the human body are generated by changes of blood distribution. The transthoracic ICG is an integrated signal covering the whole thorax and spatial resolution is poor. Comparison between both signals can be used to elucidate the source of the ICG signal. We recorded the ECG, ICG, and BCG simultaneously in healthy subjects under resting and microgravity conditions during parabolic flights. The time interval between the R-peak of the ECG and the maximum of the ICG (R-dZ/dtmax) and the time interval between the R-peak of the ECG and the I-peak in the BCG (R-I) differed significantly (p<;0.0001). The I-peak in the BCG always occurred earlier during systole than dZ/dtmax. The delay of dZ/dtmax ranged between 23 and 28 ms at rest and was lowest under microgravity conditions (12±4 ms, p<;0.02). Our results suggest that both signals have different sources. Combination of modern imaging techniques with classical non invasive approaches to detect changes of blood distribution may provide new insights into the complex interaction between blood flow and mechanocardiographic signals like the BCG.
Starting Page	7294
Ending Page	7297
File Size	437612
Page Count	4
File Format	PDF
ISBN	9781457702167
ISSN	1557170X
DOI	10.1109/EMBC.2013.6611242
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-07-03
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Impedance Electrocardiography Blood Blood flow Acceleration Electrodes
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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