NDLI: Temporal and steady state acoustic field in a cell culture well: simulation

Content Provider	IEEE Xplore Digital Library
Author	Choi, M.J. Gwan Suk Kang Kodama, T. Coleman, A.J.
Copyright Year	2013
Description	Author affiliation: Dept. of Med., Jeju Nat. Univ., Jeju, South Korea (Choi, M.J.) \|\| Grad. Sch. of Biomed. Eng., Tohoku Univ., Sendai, Japan (Kodama, T.) \|\| Dept. of Med. Phys., Guy's & St Thomas' NHS Found. Trust, London, UK (Coleman, A.J.) \|\| Interdiscipl. Postgrad. Program of Biomed. Eng., Jeju Nat. Univ., Jeju, South Korea (Gwan Suk Kang)
Abstract	The present study was to understand the true power irradiated to the cell line cultured on a culture well, in relation to the nominal power from ultrasonic transducer, and to characterize the temporal variations of the acoustic pressure exerted on the cell. Numerical simulation was carried out for a typical culture well exposed to 1 MHz continuous ultrasound generated by a circular transducer contact underneath the well. The results showed that the ultrasonic pressure exposed to the cell layer in the well was 6.7 times larger than the nominal pressure of the ultrasonic transducer. The ultrasonic pressure in the transient period rose rapidly and was widely variable, and the temporal peak was even greater than that of the steady state period. This suggests that the cells undergo characteristically different ultrasonic exposure between the transient and the steady state period.
Starting Page	1934
Ending Page	1935
File Size	1056223
Page Count	2
File Format	PDF
ISBN	9781457702167
ISSN	1557170X
DOI	10.1109/EMBC.2013.6609905
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-07-03
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Acoustics Steady-state Ultrasonic imaging Transient analysis Ultrasonic transducers Transducers In vitro
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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