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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Sung Kean Kim Tae Keun Yoo Ein Oh Deok Won Kim |
| Copyright Year | 2013 |
| Description | Author affiliation: Dept. of Med. Eng., Yonsei Univ., Seoul, South Korea (Deok Won Kim) || Grad. Program in Biomed. Eng., Yonsei Univ., Seoul, South Korea (Sung Kean Kim) || Dept. of Med., Yonsei Univ., Seoul, South Korea (Tae Keun Yoo; Ein Oh) |
| Abstract | A number of clinical decision tools for osteoporosis risk assessment have been developed to select postmenopausal women for the measurement of bone mineral density. We developed and validated machine learning models with the aim of more accurately identifying the risk of osteoporosis in postmenopausal women, and compared with the ability of a conventional clinical decision tool, osteoporosis self-assessment tool (OST). We collected medical records from Korean postmenopausal women based on the Korea National Health and Nutrition Surveys (KNHANES V-1). The training data set was used to construct models based on popular machine learning algorithms such as support vector machines (SVM), random forests (RF), artificial neural networks (ANN), and logistic regression (LR) based on various predictors associated with low bone density. The learning models were compared with OST. SVM had significantly better area under the curve (AUC) of the receiver operating characteristic (ROC) than ANN, LR, and OST. Validation on the test set showed that SVM predicted osteoporosis risk with an AUC of 0.827, accuracy of 76.7%, sensitivity of 77.8%, and specificity of 76.0%. We were the first to perform comparisons of the performance of osteoporosis prediction between the machine learning and conventional methods using population-based epidemiological data. The machine learning methods may be effective tools for identifying postmenopausal women at high risk for osteoporosis. |
| Starting Page | 188 |
| Ending Page | 191 |
| File Size | 545717 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781457702167 |
| ISSN | 1557170X |
| DOI | 10.1109/EMBC.2013.6609469 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2013-07-03 |
| Publisher Place | Japan |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Osteoporosis Support vector machines Artificial neural networks Predictive models Radio frequency Accuracy Learning systems |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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