NDLI: Cerebral blood flow changes during rat cardiopulmonary bypass and deep hypothermic circulatory arrest model: A preliminary study

Content Provider	IEEE Xplore Digital Library
Author	Lu Yuan Diansan Su Xiaohua Liu Hongyang Lu Yao Li Shanbao Tong
Copyright Year	2013
Description	Author affiliation: Dept. of Anesthesiology, Shanghai Jiao Tong Univ., Shanghai, China (Diansan Su; Xiaohua Liu) \|\| Sch. of Biomed. Eng., Shanghai Jiao Tong Univ., Shanghai, China (Lu Yuan; Hongyang Lu; Yao Li; Shanbao Tong)
Abstract	Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are important techniques often used in complex cardiac surgery for neonates and infants heart diseases. Cerebral blood flow (CBF) serves as an important physiological parameter and provides valuable hemodynamic information during the surgery. Laser speckle imaging (LSI), as an optical imaging technique, can provide full-field CBF information with a high spatiotemporal resolution. In this preliminary study, we acquired the real-time CBF images with a self-developed miniaturized head-mounted LSI system during the whole CPBillHCA rat model. Relative CBF velocity in veins and arteries in bilateral hemispheres dropped significantly during cooling period and reached to nearly zero during arrest period (n = 5). More interestingly, two rats showing more dramatic CBF variations in veins than in arteries during cooling period exhibited severe cerebral edema after surgery. The real-time full-field CBF imaging during the CPBillHCA surgery could add more insights into the operation and be utilized to study the surgical protocols with the ultimate goal ofreducing neurologic injury after surgery.
Starting Page	1807
Ending Page	1810
File Size	3119004
Page Count	4
File Format	PDF
ISBN	9781457702167
ISSN	1557170X
DOI	10.1109/EMBC.2013.6609873
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-07-03
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Surgery Arteries Veins Cooling Blood flow Speckle Rats
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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