NDLI: Estimation of cardiac output and total peripheral resistance in preterm infants by arterial waveform analysis

Content Provider	IEEE Xplore Digital Library
Author	Ying Zhang Chan, G.S.H. Tracy, M.B. Hinder, M. Redmond, S.J. Savkin, A.V. Lovell, N.H.
Copyright Year	2013
Description	Author affiliation: Westmead NICU, Sydney, NSW, Australia (Hinder, M.) \|\| Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia (Redmond, S.J.; Lovell, N.H.) \|\| Sch. of Electr. Eng. & Telecommun., Univ. of New South Wales, Sydney, NSW, Australia (Ying Zhang; Chan, G.S.H.; Savkin, A.V.) \|\| NICU Westmead Hosp., Sydney, NSW, Australia (Tracy, M.B.)
Abstract	This study investigated whether arterial blood pressure waveform analysis could be useful for estimating left ventricular outflow (LVO) and total peripheral resistance (TPR) in preterm infants. A cohort of 27 infants were studied, with 89 measurements of left ventricular outflow (LVO) using Doppler echocardiography and arterial pressure using catheters, performed in 0, 12, 24 and 36 hours after birth. TPR was computed as mean arterial pressure divided by LVO. The diastolic decay rate (1/τ) was obtained via fitting an exponential function to the last one third of each arterial pulse, with the mean rate computed from 50 pulses selected from each infant. This decay rate was considered to be inversely related to TPR while positively related to LVO. The results of regression analysis have confirmed that the diastolic decay rate had significant positive and negative relationships with LVO and TPR respectively(r = 0.383, P = 0.0002 and r = -0.379, P = 0.0002 respectively). These preliminary results demonstrated the potential utility of arterial pressure waveform analysis for estimating LVO and TPR in preterm infants, but more advanced multi-parameter models may be needed to improve accuracy of the estimation.
Starting Page	2308
Ending Page	2311
File Size	582277
Page Count	4
File Format	PDF
ISBN	9781457702167
ISSN	1557170X
DOI	10.1109/EMBC.2013.6609999
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-07-03
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Pediatrics Blood pressure Australia Heart rate Estimation Signal analysis Ultrasonic variables measurement
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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