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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Vaish, Abhishek Vijay, Vipul Vaishya, Raju Agarwal, Amit Kumar |
| Description | Author Affiliation: Vaishya R ( Department of Orthopaedics & Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi, India.); Agarwal AK ( Department of Orthopaedics & Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi, India.); Vijay V ( Department of Orthopaedics & Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi, India.); Vaish A ( Department of Orthopaedics, Sancheti Hospital, Pune, Maharashtra, India.) |
| Abstract | Multicentric giant cell tumours (GCTs) are very rare and account for less than 1% of all GCTs of bone. We report a case of a young woman with metachronous multicentric GCTs with 5 documented lesions in the same lower limb. The initial lesion started during the first trimester of pregnancy around her right pelvis, which rapidly progressed as a painful swelling with gradually restricted mobility of her right hip joint. The radiological appearance of this tumour was that of a GCT and biopsy confirmed the diagnosis. The role of positron emission tomography (PET) has been highlighted to detect occult lesions. A possible hormonal correlation for these tumours has been discussed. The patient was managed successfully by an aggressive surgical approach for knee and talar lesions, whereas repeated embolisation and denosumab injections were given to treat her pelvic lesion. |
| Volume Number | 2015 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Bone Density Conservation Agents Administration & Dosage Bone Neoplasms Diagnosis Denosumab Embolization, Therapeutic Methods Giant Cell Tumor Of Bone Lower Extremity Pathology Neoplasms, Second Primary Positron-Emission Tomography Adult Therapy Female Humans Pregnancy Treatment Outcome Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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