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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Esperança, Sofia Pacheco, Ana Paula Oliveira e Silva, Antonio Sotto Mayor, Joana |
| Description | Author Affiliation: Sotto Mayor J ( Department of Internal Medicine, Hospital de Braga, Braga, Portugal.); Pacheco AP ( Department of Internal Medicine, Hospital de Braga, Braga, Portugal.); Esperança S ( Department of Internal Medicine, Hospital de Braga, Braga, Portugal.); Oliveira e Silva A ( Department of Internal Medicine, Hospital de Braga, Braga, Portugal.) |
| Abstract | Trazodone is a second-generation atypical antidepressant exercising selective inhibitory action on the transport of serotonin. It also has an antagonist effect, similar to nefazodone, on the 5HT1 and 5HT2 receptors, probably due to the therapeutic effects of such substances. It is very effective in the treatment of depression, in anxiety and insomnia. Its known side effects mainly occur with prolonged use of daily doses of 150-200 mg. The ability to enhance drowsiness may be associated with some risk in elderly patients. This clinical case illustrates an acute extrapyramidal event induced by a low dose of trazodone. |
| Volume Number | 2015 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Basal Ganglia Diseases Chemically Induced Serotonin Uptake Inhibitors Adverse Effects Sleep Initiation And Maintenance Disorders Drug Therapy Trazodone Aged, 80 And Over Anti-Anxiety Agents Antidepressive Agents, Second-Generation Humans Male Therapeutic Use Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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