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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Hawthorne, Barney Mcdowell, Ian Prasad, Rakesh Durai, Dharmaraj |
| Description | Author Affiliation: Prasad R ( Department of Gastroenterology, Abertawe Bro Morgannwg University Health Board, Swansea, UK.); Hawthorne B ( Department of Gastroenterology, University Hospital of Wales, Cardiff, UK.); Durai D ( Department of Gastroenterology, University Hospital of Wales, Cardiff, UK.); McDowell I ( Department of Clinical Biochemistry, University Hospital of Wales, Cardiff, UK.) |
| Abstract | A 65-year-old woman with Crohn's disease, who had been on home parenteral nutrition for many years, presented with perioral paraesthesia and a burning sensation in the mouth. Initial blood tests including serum ferritin, vitamin B12 and folate, were normal apart from mild pancytopaenia. Serum copper was low, in spite of receiving regular copper in her parenteral feeds. The copper in her parenteral feeds was increased initially, but when it did not improve, she was started on weekly intravenous copper infusions. She was using dental adhesive, which had zinc in it, and a possibility that this was causing her copper deficiency was raised. Serum zinc levels were normal, but urinary zinc was very high. The patient was advised to use zinc-free dental adhesive and her copper level returned to normal within a few months with normalisation of her pancytopaenia, and partial resolution of her oral paraesthesia. |
| Volume Number | 2015 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Copper Deficiency Dental Cements Adverse Effects Zinc Urine Aged Crohn Disease Diet Therapy Female Humans Parenteral Nutrition, Home Paresthesia Etiology Blood Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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