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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Mahfood Haddad, Toufik Vallabhajosyula, Saraschandra Vivekanandan, Renuga Sundaragiri, Pranathi Rao |
| Description | Author Affiliation: Mahfood Haddad T ( Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, USA.); Vallabhajosyula S ( Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, USA.); Sundaragiri PR ( Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, USA.); Vivekanandan R ( Division of Infectious Diseases, Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, USA.) |
| Abstract | Pseudoaneurysms are vessel wall ruptures, that are often mistaken for deep vein thrombosis (DVT). A middle-aged man presented with right leg pain, swelling and erythema. His history was significant for persistent Staphylococcus aureus bacteraemia. Ultrasound revealed subacute DVT and laboratory parameters were suggestive of sepsis. He was started on intravenous heparin and antimicrobials. Owing to persistent anaemia despite blood transfusion, MRI of the right thigh was obtained. It revealed a 13×17â cm superficial femoral artery infected mycotic pseudoaneurysm (MPA) with a fresh haematoma. The patient underwent arterial ligation and extensive debridement. Intraoperative cultures revealed daptomycin-resistant vancomycin-intermediate S. aureus (VISA) and he was managed with 6â weeks of intravenous ceftaroline. MPAs are most common in the femoral artery and form <1% of aneurysms. Therapy involves surgical debridement and prolonged antimicrobials. VISA causing MPA is associated with worse outcomes. We report the first time use of ceftaroline in the management of a VISA MPA. |
| Volume Number | 2015 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Aneurysm, False Microbiology Bacteremia Femoral Artery Mycoses Staphylococcus Aureus Diagnosis Drug Therapy Anti-Bacterial Agents Therapeutic Use Cephalosporins Debridement Diagnosis, Differential Drug Resistance, Microbial Humans Ligation Male Middle Aged Therapy Drug Effects Thigh Blood Supply Vancomycin Pharmacology Venous Thrombosis Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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