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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Takei, Kentarou Nakamura, Masashi Shimizu, Hiroshi Sato, Mineshige |
| Description | Author Affiliation: Takei K ( Department of Neurology, Osaki Citizens' Hospital, Osaki, Japan.); Sato M ( Department of Neurology, Osaki Citizens' Hospital, Osaki, Japan.); Nakamura M ( Department of Neurology, Osaki Citizens' Hospital, Osaki, Japan.); Shimizu H ( Department of Neurology, Osaki Citizens' Hospital, Osaki, Japan.) |
| Abstract | Transverse myelitis (TM) with systemic lupus erythematosus (SLE) has been linked to the presence of autoantibodies (eg, antiaquaporin 4 (AQP4) and anticardiolipin (aCL)) and SLE-induced secondary vasculitis, but the aetiology remains incompletely understood. A 48-year-old Japanese man with a 6-year history of poorly controlled SLE had stopped glucocorticoid therapy 1 year before admission. 3 days before admission, he developed flaccid paraplegia. Spinal MRI showed a longitudinally hyperintense T2 grey matter lesion from the level of Th4 to the conus medullaris, which was considered longitudinally extensive TM (LETM). We administered steroid pulse therapy (methyl-prednisolone 1000 mg/day) for 3 days and prednisolone 50 mg/day. The patient's flaccid paralysis gradually improved. We concluded that the patient's TM was caused by SLE flare-up, even though we could not completely rule out antiphospholipid syndrome. SLE myelitis is relatively rare and many aetiologies are possible for TM in SLE. |
| Volume Number | 2015 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Autoantibodies Analysis Lupus Erythematosus, Systemic Complications Myelitis, Transverse Immunology Receptors, N-Methyl-D-Aspartate Diagnosis, Differential Follow-Up Studies Humans Drug Therapy Male Middle Aged Diagnosis Treatment Outcome Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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