Multicentric Giant Cell Tumor of Bone: Metachronous Presentation-a Case Report.

Content Provider	Europe PMC
Author	Sapiai, Nur Asma Wan Fatihah, W. S. Faisham, W. I. Anani Aila, M. Z.
Abstract	Giant cell tumors (GCT) of bone are a benign aggressive tumor with features of frequent local recurrence. It has the potential for metastasis and malignant transformation. GCT of bone represents about 4–9.5% of primary bone tumors. Metachronous GCT happen in less than 1% while metastatic spread in these lesions is very uncommon. Furthermore, reports of multicentric metachronous GCT are very rare in literature. We present a case of a 35-year-old male patient, who suffered from multicentric metachronous GCT, which involved the radius, humerus, femur, and pelvic with pulmonary metastasis. Local control by multiple resections of the tumor and chemotherapy for pulmonary metastases was able to control the disease with long-term survival and good functional outcome. These tumors had a typical radiological appearance and the diagnosis was confirmed on histopathology. Long follow-up needed in this case in view the illness occurs for long period.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8716647&blobtype=pdf
ISSN	09757651
Volume Number	12
DOI	10.1007/s13193-021-01331-7
PubMed Central reference number	PMC8716647
Issue Number	Suppl 2
Issue Number	suppl 2
PubMed reference number	35035165
Journal	Indian Journal of Surgical Oncology [Indian J Surg Oncol]
e-ISSN	09766952
Language	English
Publisher	Springer India
Publisher Date	2021-05-17
Publisher Place	New Delhi
Access Restriction	Open
Rights License	© Indian Association of Surgical Oncology 2021
Subject Keyword	Bone tumor Multicentric metachronous giant cell tumors Pulmonary metastasis
Content Type	Text
Resource Type	Article
Subject	Surgery Oncology