NDLI: Biosensing with Localized Surface Plasmon Resonance Based on Cap-Shaped Gold Nano-Particles

Content Provider	IEEE Xplore Digital Library
Author	Zhong Cao Fu-Chun Gong Xi-Xi Huang Shu-Zhen Tan Takei, H. Pipper, J.
Copyright Year	2008
Description	Author affiliation: Sch. of Chem. & Environ. Eng., Changsha Univ. of Sci. & Technol., Changsha (Zhong Cao; Fu-Chun Gong; Xi-Xi Huang; Shu-Zhen Tan)
Abstract	In this paper, the optical biosensors based on cap- shaped gold nano-particles have been constructed by evaporating gold on polystyrene and silica microspheres to form Au caps, which show a novel localized surface plasmon resonance (LSPR). The gold surface on silica spheres modified with a carboxymethyl dextran layer was used for sensing of anti-avidin D with a detection limit of 5.0 $nmolldrL^{-1}$ and a sensitivity of 3.4 times $10^{-3}$ $nmldrLldrnmol^{-1},$ which was based on surface-bound avidin molecule. Furthermore, a double stranded DNA (dsDNA) with a binding site of hexa sequence AGGTCA for a nuclear receptor, retinoid X receptor beta (RXRbeta), has been successfully immobilized on gold surface via a specific interaction between biotin moiety and streptavidin, and applied to selective recognition of small molecule nuclear ligands like 9-cis retinoic acid.
Starting Page	1596
Ending Page	1598
File Size	1020758
Page Count	3
File Format	PDF
ISBN	9781424417476
DOI	10.1109/ICBBE.2008.727
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-05-16
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Silicon compounds Proteins Gold Biomedical optical imaging Molecular biophysics Plasmons Resonance Biosensors Optical sensors Optical surface waves
Content Type	Text
Resource Type	Article

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