NDLI: Motion correction in treadmill first-pass radionuclide angiography

Content Provider	IEEE Xplore Digital Library
Author	Sun, L. Lacy, J.L. Martin, C.S. Nayak, N. Clark, J.W.
Copyright Year	2002
Description	Author affiliation: Dept. of Electr. & Comput. Eng., Rice Univ., Houston, TX, USA (Sun, L.)
Abstract	High-quality, first-pass radionuclide angiography (RNA) of the human heart is performed to study left ventricular function of patient during peak treadmill exercise, by means of a Multiwire Gamma Camera (MWGC) and intravenous injection of ultrashort-lived radionuclide Tantalum-178. The prognostic value of treadmill RNA in patients with coronary artery disease (CAD) is significant compared with other clinical and catheterization variables, but patient motion and resulting image blurring during the treadmill exercise can degrade resolution and introduce serious image distortion. We have developed a correction method which incorporates an electromagnetic motion tracking to monitor the movement of left ventricle (LV) center, based on the real-time six-dimensional position and orientation of the sensor attached on patient's back, and LV center location in patient's chest contour. The method was evaluated in dynamic phantom simulations using an Am-241 point source worn by a volunteer exercising at Bruce Level IV. Accuracy of correction was assessed by calculating root mean square (RMS) error of the locations of the maximum activity pixel (centroid) in uncorrected and corrected images, and by visual comparison of corrected versus uncorrected image sequences. The results show that the motion artifact can be effectively removed with source movement simulating that of a patient's heart at peak exercise. We conclude that this method shows promise to compensate for body motion under clinical MWGC imaging conditions during treadmill exercise.
Starting Page	913
Ending Page	914
File Size	154457
Page Count	2
File Format	PDF
ISBN	0780376129
ISSN	1094687X
DOI	10.1109/IEMBS.2002.1106202
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-23
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Angiography RNA Heart Coronary arteriosclerosis Humans Cameras Catheterization Degradation Image resolution Tracking
Content Type	Text
Resource Type	Article

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