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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Xiao, J. Jiang, A-A Bai, L. Li, M. Z. Liu, H. F. Li, X. W. |
| Description | Country affiliation: China Author Affiliation: Jiang AA ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China.); Li MZ ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China.); Liu HF ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China.); Bai L ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China.); Xiao J ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China.); Li XW ( Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an, Sichuan, China xuewei.li@sicau.edu.cn.) |
| Abstract | The balance between biosynthesis and oxidation of fatty acids determines adipose deposition in mammals. Obese and lean pigs show obvious differences in total adipose mass and therefore offer an attractive model for comparative studies. We found that obese Rongchang pigs, when compared with lean Landrace pigs, exhibited significantly higher mRNA levels for five genes encoding acyl-CoA dehydrogenases involved in mitochondrial fatty-acid ß-oxidation in eight different adipose tissues. These changes in gene expression were positively correlated with adipocyte volume in the eight adipose tissues. Based on these results, we hypothesize that acyl-CoA dehydrogenase genes participate in the regulation of fat mass in pigs. |
| e-ISSN | 16765680 |
| Journal | Genetics and Molecular Research |
| Issue Number | 1 |
| Volume Number | 13 |
| Language | English |
| Publisher | Fundação de Pesquisas Científicas de Ribeirão Preto |
| Publisher Date | 2014-03-17 |
| Publisher Place | Brazil |
| Access Restriction | Open |
| Subject Keyword | Acyl-coa Dehydrogenases Biosynthesis Adipose Tissue Enzymology Obesity Genetics Adipocytes Metabolism Animals Breeding Fatty Acids Gene Expression Regulation Veterinary Oxidation-reduction Rna, Messenger Sus Scrofa Swine Growth & Development Research Support, Non-u.s. Gov't Discipline Genetics Discipline Molecular Biology Discipline Bioinformatics |
| Content Type | Text |
| Resource Type | Article |
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