NDLI: Fully-integrated plastic-antibody-based biochips with easy-to-attach vacuum sources for C-reactive protein sensing

Content Provider	IEEE Xplore Digital Library
Author	Cheng-Han Tsai Wen Chung Wei-Han Wang Kuan-Wen Chen Chien-Chong Hong Chie-Pein Chen
Copyright Year	2013
Description	Author affiliation: BioMEMS & NanoBiosystems Lab., Nat. Tsing Hua Univ., Hsinchu, Taiwan (Cheng-Han Tsai; Wen Chung; Wei-Han Wang; Kuan-Wen Chen; Chien-Chong Hong) \|\| Dept. of Obstetrics & Gynecology, Mackay Memorial Hosp., Taipei, Taiwan (Chie-Pein Chen)
Abstract	This paper presents a novel fully-integrated plastic-antibody-based biochip with easy-to-attach vacuum source for C-reactive protein sensing. Micropumps are the most popular devices for the microfluidic system especially in point-of-care devices. However, because the difficulty of miniaturizing the pump, most micropumps are complicated in the structure/assembly or not suitable for the disposable devices. In this paper, a fully-integrated biochip including easy-to-attach vacuum source made of shape memory polymer and a plastic antibody film were developed. By the 2 sets of vacuum source and mini-heater, the biochip could achieve two-stage microfluidic control with easy process. The vacuum sources show great performance in the experiment, and with the advantage of compact, simple structure, and east-to-attach with the biochip. The flow rate driven by our vacuum source is up to 15 μl/ml.
Starting Page	1217
Ending Page	1220
File Size	1506215
Page Count	4
File Format	PDF
ISBN	9781467359832
ISSN	21641641
DOI	10.1109/Transducers.2013.6626993
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-06-16
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Proteins Microfluidics Sensors Plastics Vacuum systems Films Polymers Point-of-Care microfludics Micropump vacuum source Shape Memory Polymer C-Reactive Protein
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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