NDLI: Long term LFP measurements with ultra-fine neural electrodes embedded in porous resorbable carrier

Content Provider	IEEE Xplore Digital Library
Author	Ceyssens, F. van Kuyck, K. Nuttin, B. Puers, R.
Copyright Year	2013
Description	Author affiliation: Dept. ESAT-MICAS, KU Leuven, Leuven, Belgium (Ceyssens, F.; Puers, R.) \|\| Exp. Neurosurg. & Neuroanatomy, KULeuven, Leuven, Belgium (van Kuyck, K.; Nuttin, B.)
Abstract	We have developed a novel type of neural electrode array for future brain-machine interfaces (BMIs) or neural prosthesis requiring high resolution recording and stimulation on the cortex. The microelectrode arrays developed comprise of a down to 5 μm thin stack of platinum and polyimide or Parylene C insulation, which is finely microstructured for increased flexibility. The electrode stack is temporarily reinforced with a matrix of porous chitosan, which resorbs after implantation. This design ensures low invasiveness and mechanical irritation during prolonged use, while the chitosan matrix ensures the implant is stiff enough for practical handling during the implantation procedure and is resorbed afterwards. Furthermore, it adds haemostatic and antiseptic properties to the implant. The design and fabrication process are presented. In vitro and long-term in vivo test results are illustrate the ability to measure an evoked physiological response in a period of up to 12 months. Finally, the concept of using porous, scaffold-like materials as main constituent of neural implants is discussed.
Starting Page	868
Ending Page	871
File Size	699934
Page Count	4
File Format	PDF
ISBN	9781467359832
ISSN	21641641
DOI	10.1109/Transducers.2013.6626905
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-06-16
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrodes Arrays Implants Fabrication Materials In vivo Physiology chronic Neural electrode neural electrode array BCI BMI ECoG chitosan scaffold neural recording neural stimulation thin film
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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