NDLI: Fabrication of multi-layer, high-density micro-electrode arrays for neural stimulation and bio-signal recording

Content Provider	IEEE Xplore Digital Library
Author	Suaning, G.J. Schuettler, M. Ordonez, J.S. Lovell, N.H.
Copyright Year	2007
Description	Author affiliation: Sch. of Eng., Newcastle Univ., Callaghan, NSW (Suaning, G.J.)
Abstract	The electrode-tissue interface is of principal importance in neuroprosthesis. Indeed the successes of the cochlear implant and other therapeutic devices are directly attributable to the design and fabrication techniques of their interfaces with neural tissue, that is, the electrode or electrode array. Traditional fabrication techniques are often labor-intensive and do not lend themselves to automation thereby increasing the cost of the electrode, and owing to fabrication variability, potentially compromising the reliability of the devices incorporating them. Exacerbating the difficulties in electrode fabrication further is the fact that only a handful of materials have been demonstrated to be biologically inert. These same materials are often among the most difficult to utilize in the fabrication of neural electrodes. In the present paper, a new methodology for automated fabrication of high-density electrode arrays is presented. Using exclusively biologically-inert raw materials, laser machining techniques combined with multiple layer structuring is shown to achieve feature sizes of the order of 25 mum. As an illustrative example, a 98 electrode array for interfacing with surviving retinal tissue through a visual prosthesis for the blind is presented. Overall dimensions of the array are of the order of 8.7 times 9.4 mm, consistent with approximately 25 degrees of visual field.
Starting Page	5
Ending Page	8
File Size	639303
Page Count	4
File Format	PDF
ISBN	1424407915
DOI	10.1109/CNE.2007.369597
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-05-02
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cochlear implants Automation Costs vision prosthesis Machining Retina Raw materials Biological materials Electrodes Optical device fabrication retina neuroprosthesis Optical materials neural interface electrode array
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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