NDLI: Fully automatic segmentation of the open mitral leaflets in 3D transesophageal echocardiographic images using multi-atlas label fusion and deformable medial modeling

Content Provider	IEEE Xplore Digital Library
Author	Pouch, A.M. Hongzhi Wang Yushkevich, P.A. Takabe, M. Jackson, B.M. Gorman, J.H. Gorman, R.C. Sehgal, C.M.
Copyright Year	2012
Description	Author affiliation: Univ. of Pennsylvania, Philadelphia, PA, USA (Pouch, A.M.; Hongzhi Wang; Yushkevich, P.A.; Takabe, M.; Jackson, B.M.; Gorman, J.H.; Gorman, R.C.; Sehgal, C.M.)
Abstract	The goal of this work is to develop a fully automatic method for segmentation of the mitral leaflets in 3D transesophageal echocardiographic (3D TEE) images. The method combines complementary probabilistic segmentation and geometric modeling techniques to generate 3D patient-specific reconstructions of the mitral leaflets and annulus from 3D TEE image data with no user interaction. In the model-based segmentation framework, mitral leaflet geometry is described with 3D continuous medial representation (cm-rep). To capture leaflet geometry in a target 3D TEE image, a pre-defined cm-rep template of the mitral leaflets is deformed such that the negative log of a Bayesian posterior probability is minimized. The likelihood of the objective function is given by a probabilistic segmentation of the mitral leaflets generated by multi-atlas joint label fusion, while the validity constraints and regularization terms imposed by cm-rep act as shape priors that preserve leaflet topology and constrain model fitting. The method is tested on ten 3D TEE images of human mitral leaflets at mid-diastole, using manual segmentation as the gold standard.
Starting Page	220
Ending Page	223
File Size	1511549
Page Count	4
File Format	PDF
ISBN	9781467345613
ISSN	19485719
e-ISBN	9781467345620
DOI	10.1109/ULTSYM.2012.0055
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-10-07
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Image segmentation Valves Deformable models Geometry Solid modeling Joints Manuals multi-atlas segmentation 3D ultrasound mitral valve deformable medial modeling
Content Type	Text
Resource Type	Article

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