NDLI: A microfluidic “treadmill” for sperm selective trapping according to motility classification

Content Provider	IEEE Xplore Digital Library
Author	Qiu, T. Han, C. Ma, R. Xie, L. Li, Z. Su, K. Wang, L. Huang, G. Wang, J. Qiao, J. Xing, W. Cheng, J.
Copyright Year	2011
Description	Author affiliation: Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China (Qiu, T.; Han, C.; Ma, R.; Xie, L.; Li, Z.; Huang, G.; Xing, W.; Cheng, J.) \|\| National Engineering Research Center for Beijing Biochip Technology, China (Wang, L.) \|\| Center of Reproduction Medicine, Department of Obstetrics and Gynecology, Third Hospital of Peking University, Beijing, China (Qiao, J.) \|\| Shanxi Key Laboratory of Ecological Animal Science and Environmental Medicine, Shanxi Agricultural University, Taigu, China (Su, K.; Wang, J.)
Abstract	Sperm motility analysis is an indispensable test in male infertility diagnosis. The current microscopic method cannot select the sperm of specific velocity for further in vitro Fertilization (IVF) usage or research purposes. Here, we report a novel and simple microfluidic device capable of balancing sperm's swimming speed with local flow velocity. The results suggested that sperm motility was quantitatively graded and sperm with different average straight line velocity (VSL) 40.5 ± 3.0, 27.2 ± 0.6 and 18.7 ± 0.6 µm/s respectively were automatically trapped in corresponding regions. Sperm motility classification (SMC) and sperm trapping may facilitate both the diagnosis of male infertility and further studies on sperm physiological behavior.
Starting Page	1320
Ending Page	1323
File Size	1296193
Page Count	4
File Format	PDF
ISBN	9781457701573
e-ISBN	9781457701566
DOI	10.1109/TRANSDUCERS.2011.5969411
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-06-05
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Microfluidics Fluids Charge carrier processes Mice Microscopy Microchannel microfluidics sperm motility cell trapping
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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