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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Jing Jin Dauwels, J. Cash, S. |
| Copyright Year | 2014 |
| Description | Author affiliation: Sch. of Electr. & Electron. Eng., Nanyang Technol. Univ., Singapore, Singapore (Jing Jin; Dauwels, J.) || Neurology Dept., Massachusetts Gen. Hosp., Boston, MA, USA (Cash, S.) |
| Abstract | Up to 30% of epileptic patients have seizures poorly controlled with anti-epileptic drugs alone. Surgical therapy might be beneficial to patients who respond poorly to drug treatments. It is therefore crucial to accurately localize the seizure focus. Neurologists rely heavily on seizures to determine the focus. The invasive recordings usually continue for days or weeks, which is costly and entails significant risk for the patients. In this paper, techniques are developed to localize the seizure focus using brief interictal intracranial EEG (iEEG). A supervised learning paradigm is utilized making use of features extracted from interictal iEEG on multiple referential montages. Analysis of 14 epileptic patients (implanted with depth electrodes) shows that iEEG features such as slowing, ripples, spikes, and local synchrony measures are strongly correlated to the seizure focus. These procedures may allow reliable localization of the seizure focus from brief interictal iEEG, which in turn may lead to shorter hospitalizations. |
| Sponsorship | IEEE Eng. Med. Biol. Soc. |
| Starting Page | 4439 |
| Ending Page | 4442 |
| File Size | 624424 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424479290 |
| ISSN | 1557170X |
| DOI | 10.1109/EMBC.2014.6944609 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-08-26 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Electroencephalography Hafnium compounds Electrodes Epilepsy Educational institutions Sensitivity Oscillators |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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