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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Charlton, P. Smith, J. Camporota, L. Beale, R. Alastruey, J. |
| Copyright Year | 2014 |
| Description | Author affiliation: Dept. of Biomed. Eng., King's Coll. London, London, UK (Charlton, P.; Alastruey, J.) || Dept. of Critical Care Med., Guy's & St Thomas' NHS Found. Trust, London, UK (Smith, J.; Camporota, L.; Beale, R.) |
| Abstract | Algorithms for estimating cardiac output (CO) from the arterial blood pressure wave have been observed to be inaccurate during changes in vascular tone. Many such algorithms are based on the Windkessel model of the circulation. We investigated the optimal analytical approaches and assumptions that make up each algorithm during changes in vascular tone. Several analytical approaches and assumptions were evaluated on data from 15 critically ill patients by comparison with thermodilution measurements. We found that the most accurate algorithms assumed a constant compliance for the duration of the beat. They produced a percentage error of ±31% by maintaining the compliance and outflow terms in the Windkessel model. For any algorithm, the following assumptions gave highest accuracy: (i) outflow pressure into the microcirculation is zero; (ii) end of systole is identified using the second derivative of pressure. None of the tested algorithms reached the clinically acceptable accuracy of ±30%. |
| Sponsorship | IEEE Eng. Med. Biol. Soc. |
| Starting Page | 3759 |
| Ending Page | 3762 |
| File Size | 917617 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424479290 |
| ISSN | 1557170X |
| DOI | 10.1109/EMBC.2014.6944441 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-08-26 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Accuracy Resistance Arterial blood pressure Mathematical model Monitoring Calibration Algorithm design and analysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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