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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Hunyadi, B. Tousseyn, S. Dupont, P. Van Huffel, S. Van Paesschen, W. De Vos, M. |
| Copyright Year | 2014 |
| Description | Author affiliation: Dept. of Electr. Eng., KU Leuven, Leuven, Belgium (Hunyadi, B.; Van Huffel, S.) || Lab. for Epilepsy Res., KU Leuven, Leuven, Belgium (Tousseyn, S.; Dupont, P.; Van Paesschen, W.) || Dept. of Psychol., Univ. of Oldenburg, Oldenburg, Germany (De Vos, M.) |
| Abstract | EEG-correlated fMRI analysis has proven to be useful in localizing regions of BOLD activation related to epileptic activity. However, as EEG does not always provide reliable information, purely fMRI-based data-driven techniques are invaluable. Recently, we have shown that independent component analysis (ICA) can extract sources related to the epileptic network even in such EEG-negative cases [1]. Moreover, these sources were shown to be informative with respect to the seizure onset zone (SOZ). In order to utilize this concept in clinical practice in a prospective manner, this work aims at developing an automatic technique for selecting the epileptic sources. The proposed approach applies a cascade of two classifiers. In the first step artifact related sources are discarded. In the second step the sources are characterized by four discriminative features and epileptic sources are selected from among other BOLD-related components. Our technique reaches a promising 77% specificity and provides concordant sources with the EEG-correlated fMRI activation maps or with the SOZ in 71% of the cases. |
| Sponsorship | IEEE Eng. Med. Biol. Soc. |
| Starting Page | 3853 |
| Ending Page | 3856 |
| File Size | 783929 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424479290 |
| ISSN | 1557170X |
| DOI | 10.1109/EMBC.2014.6944464 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-08-26 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Integrated circuits Epilepsy Electroencephalography Feature extraction Sensitivity Dictionaries Independent component analysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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