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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Chen, X. Cui, D.F. Zhang, L.L. |
| Copyright Year | 2009 |
| Description | Author affiliation: State Key Lab. of Transducer Tech., Inst. of Electronics, Chinese Academy of Sciences, 100190 Beijing, China (Chen, X.; Cui, D.F.; Zhang, L.L.) |
| Abstract | In this manuscript we designed and fabricated two types of microfluidic chips for plasma isolation from whole blood by using micro/nano structures. One type of the microchips was designed based on the principle of crossflow filtration, while the other was based on plasma skimming effect. The microchips were fabricated by MEMS technology, which were made of a silicon wafer and a PDMS-glass cover. The fabrication parameters were demonstrated and optimized for the both types of chips. These microfluidic chips used for plasma isolation has the potential to integrate into micro total analytical system (μTAS) with the advantages of low cost, short analytical time, disposability, low reagent and sample consumption, which will create a microanalysis system for point-of-care diagnostics. |
| Starting Page | 98 |
| Ending Page | 101 |
| File Size | 2767618 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424446292 |
| DOI | 10.1109/NEMS.2009.5068535 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-01-05 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Fabrication Microfluidics Blood Plasma applications Filtration Plasma diagnostics Plasma devices Microchannel Micromechanical devices Isolation technology MEMS microfluidic plasma isolation micro/nano structures |
| Content Type | Text |
| Resource Type | Article |
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