NDLI: Theoretical Analytical Flow Model in Hollow Microneedles for Non-forced Fluid Extraction

Content Provider	IEEE Xplore Digital Library
Author	Ran Liu Xiaohao Wang Yanying Feng Guangzhi Wang Jing Liu Hui Ding
Copyright Year	2006
Description	Author affiliation: Dept. of Biomed. Eng., Tsinghua Univ., Beijing (Ran Liu)
Abstract	In a hollow microneedles for non-force fluid extraction and transfer, under the viscosity and capillary force, the fluid flow velocity varied following time. The fluid mechanical analysis couldn't apply the steady pipe flow model. In this paper, based on Newtonian fluid, a transient flow theoretical model was built to interpret microfluidic properties in the microneedle with the rectangular cross section for non-force fluid extraction and transfer, and the analytical solution for the marching position of fluid flow was obtained in order to study the relation between the flow variables and physical properties in pipe flow of a Newtonian fluid in the microneedle. The contact angles between the open surface of the microneedle and the different fluids, which were water, plasma, serum and whole blood, were measured using the CCD to approximate as the contact angles of the internal surface. For faster fluid filling into the microneedles, the length width ratio of the section of microchannel was optimized to radic 2 +1
Starting Page	1039
Ending Page	1042
File Size	1137661
Page Count	4
File Format	PDF
ISBN	1424401399
DOI	10.1109/NEMS.2006.334607
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Analytical models Fluid flow Viscosity Transient analysis Microfluidics Plasma properties Plasma measurements Blood Charge coupled devices Filling fluid extraction flow model microneedles
Content Type	Text
Resource Type	Article

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