NDLI: Integrated Sample Injection Chip for Micro-HPLC

Content Provider	IEEE Xplore Digital Library
Author	Ezaki, T. Yamazaki, T. Yasuda, S. Yagi, T.
Copyright Year	2006
Description	Author affiliation: NEMS Platform Res. Div., Canon Inc., Atsugi (Ezaki, T.; Yamazaki, T.; Yasuda, S.; Yagi, T.)
Abstract	In this paper we present a novel sample injection chip. Microvalves and microchannels are integrated on the chip. The valve is a passive lowpass valve that allows a liquid flow at a low flow rate and prohibits it when the flow rate exceeds a threshold. We can control the injection volume by changing the channel design. The chip consists of a channel substrate, an upper valve substrate and an under valve substrate. These substrates are separately fabricated and bonded by using MEMS techniques. The chip, not to leak at a pressure difference of 5.0 MPa, was successfully applied to high performance liquid chromatography (HPLC). A specific volume of sample (100 nl) was injected to the HPLC column. The results show that the sample injection chip has the possibility of being used in the micro-HPLC systems.
Starting Page	979
Ending Page	983
File Size	4753042
Page Count	5
File Format	PDF
ISBN	1424401399
DOI	10.1109/NEMS.2006.334578
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Valves Microvalves Fluid flow Bonding Systems engineering and theory Yagi-Uda antennas Nanoelectromechanical systems Microchannel Micromechanical devices Chemicals HPLC sample injection microvalve passive valve low pass valve
Content Type	Text
Resource Type	Article

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