NDLI: Lab-on-a-chip sensor for measuring zinc in blood serum

Content Provider	IEEE Xplore Digital Library
Author	Jothimuthu, P. Wilson, R.A. Sukavasi, S. Herren, J. Wong, H. Beyette, F.R. Heineman, W.R. Papautsky, I.
Copyright Year	2010
Description	Author affiliation: Department of Biomedical Engineering, University of Cincinnati, OH USA (Herren, J.) \|\| School of Electronic and Computing Systems, University of Cincinnati, OH USA (Jothimuthu, P.; Sukavasi, S.; Beyette, F.R.; Papautsky, I.) \|\| Department of Chemistry, University of Cincinnati, OH USA (Wilson, R.A.; Heineman, W.R.) \|\| Department of Pediatrics, Cincinnati Children's Hospital Medical Center, OH USA (Wong, H.)
Abstract	This work describes the development of an electrochemical sensor for point-of-care measurement of zinc in blood serum. The sensor is based on the anodic stripping voltammetry (ASV) and consists of a three-electrode system including bismuth working electrode, an on-chip Ag/AgCl reference electrode, and a Au auxiliary electrode. The demonstrated sensor allowed rapid and accurate measurement of zinc in the physiological range (65∼95 µg/dL). Thus, the developed lab-on-a-chip sensor permits measurement of Zn in blood serum with reduced sample volumes (200 µL from a drop of blood from a finger prick) and reduced turnaround time (10∼20 min). Ultimately, this system will permit the quantification of Zn at the bedside of critically ill patients.
Starting Page	1222
Ending Page	1225
File Size	728462
Page Count	4
File Format	PDF
ISBN	9781424481705
ISSN	19300395
e-ISBN	9781424481699
e-ISBN	9781424481682
DOI	10.1109/ICSENS.2010.5690623
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-11-01
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Zinc Electrodes Bismuth Electric potential Current measurement Blood
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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