NDLI: Supersampling in PET. A concept for improvement of the resolution of positron emission tomography

Content Provider	IEEE Xplore Digital Library
Author	Assentoft, J.E. Thomsen, J.S. Andreasen, A.
Copyright Year	2010
Description	Author affiliation: Department of Nuclear Medicine & PET/CT, Aalborg University Hospital, 9000, Denmark (Assentoft, J.E.) \|\| Department of Connective Tissue Biology, Institute of Anatomy, University of Aarhus, 8000, Denmark (Thomsen, J.S.) \|\| Department of Cell Biology, University of Aarhus, 8000, Denmark (Andreasen, A.)
Abstract	At present, the maximum spatial resolution of state-of-the-art PET scanners is not better than 5 mm, whereas the maximum resolution obtained in the resulting images is approximately 10 mm. At least some of this difference is a result of an inherent, complex noise component that can be eliminated using “supersampling”. The aim of the study was to apply the supersampling technique to PET image recordings to lower the noise and to improve the in-plane resolution of the recorded images. A standardized phantom was investigated with the supersampling technique. In addition to the standard CT and PET series, 14 further PET series were recorded with the phantom at exactly the same position, and 4 further series were recorded with the phantom placed in another well defined position. After merging corresponding images, the image noise index and the image resolution are both substantially improved. The suggested PET image recording and processing technique provides a substantial increase in PET image quality without exposing the patient to any additional radiation, and might therefore become a powerful tool for investigative as well as diagnostic purposes.
Starting Page	3622
Ending Page	3625
File Size	529862
Page Count	4
File Format	PDF
ISBN	9781424441235
ISSN	1557170X
DOI	10.1109/IEMBS.2010.5627447
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-08-31
Publisher Place	Argentina
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Noise Phantoms Computed tomography Image quality Spatial resolution
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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