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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Garcia, P.A. Neal, R.E. Rossmeisl, J.H. Davalos, R.V. |
| Copyright Year | 2010 |
| Description | Author affiliation: Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg 24061 USA (Rossmeisl, J.H.) || Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Blacksburg, 24061 USA (Garcia, P.A.; Neal, R.E.; Davalos, R.V.) |
| Abstract | Non-thermal irreversible electroporation (N-TIRE) is a new minimally invasive technique to kill undesirable tissue. We build on our previous intracranial studies in order to evaluate the possibility of using N-TIRE for deep intracranial disorders. In this manuscript we describe a minimally invasive computed tomography (CT) guided N-TIRE procedure in white matter. In addition, we report the electric field threshold needed for white matter ablation (630 – 875 V/cm) using four sets of twenty 50 µs pulses at a voltage-to-distance ratio of 1000 V/cm. We also confirm the non-thermal aspect of the technique with real time temperature data measured at the electrode-tissue interface. |
| Starting Page | 2743 |
| Ending Page | 2746 |
| File Size | 702141 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424441235 |
| ISSN | 1557170X |
| DOI | 10.1109/IEMBS.2010.5626371 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-08-31 |
| Publisher Place | Argentina |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Lesions Electrodes Electric fields Magnetic resonance imaging Conductivity Temperature measurement Tires |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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