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Content Provider | IEEE Xplore Digital Library |
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Author | Sugo, Y. Ukawa, T. Takeda, S. Ishihara, H. Kazama, T. Takeda, J. |
Copyright Year | 2010 |
Description | Author affiliation: Dept. of Anesthesiology, School of Medicine, Keio University, Tokyo, Japan (Takeda, J.) || Dept. of Anesthesiology, National Defense Medical College, Saitama, Japan (Kazama, T.) || Dept. of Clinical Engineering, Tokyo Univ. of Technology, Japan (Takeda, S.) || Dept. of Anesthesiology, Hirosaki Univ., Graduate School of Medicine, Aomori, Japan (Ishihara, H.) || Nihon Kohden Corp., 1-31-4 Nishi-Ochiai, Shinjuku-ku, Tokyo, Japan (Sugo, Y.; Ukawa, T.) |
Abstract | Monitoring cardiac output (CO) is important for the management of patient circulation in an operation room (OR) or intensive care unit (ICU). We assumed that the change in pulse wave transit time (PWTT) obtained from an electrocardiogram (ECG) and a pulse oximeter wave is correlated with the change in stroke volume (SV), from which CO is derived. The present study reports the verification of this hypothesis using a hemodynamic analysis theory and animal study. PWTT consists of a pre-ejection period (PEP), the pulse transit time through an elasticity artery (T1), and the pulse transit time through peripheral resistance arteries (T2). We assumed a consistent negative correlation between PWTT and SV under all conditions of varying circulatory dynamics. The equation for calculating SV from PWTT was derived based on the following procedures. 1. Approximating SV using a linear equation of PWTT. 2. The slope and y-intercept of the above equation were determined under consideration of vessel compliance (SV was divided by Pulse Pressure (PP)), animal type, and the inherent relationship between PP and PWTT. Animal study was performed to verify the above-mentioned assumption. The correlation coefficient of PWTT and SV became r = −0.710 (p < 0.001), and a good correlation was admitted. It has been confirmed that accurate continuous CO and SV measurement is only possible by monitoring regular clinical parameters (ECG, SpO2, and NIBP). |
Starting Page | 2853 |
Ending Page | 2856 |
File Size | 516514 |
Page Count | 4 |
File Format | |
ISBN | 9781424441235 |
ISSN | 1557170X |
DOI | 10.1109/IEMBS.2010.5626343 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2010-08-31 |
Publisher Place | Argentina |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Correlation Monitoring Electrocardiography Arteries Animals Blood pressure Blood |
Content Type | Text |
Resource Type | Article |
Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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