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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Takahashi, M. Ito, A. Kajihara, T. Matsuo, H. Arai, T. |
| Copyright Year | 2010 |
| Description | Author affiliation: School of Fundamental Science and Technology, Graduate School of Science and Technology, KEIO University (Japan) (Takahashi, M.; Ito, A.; Kajihara, T.; Matsuo, H.; Arai, T.) |
| Abstract | The purpose of this study is to investigate transient process of the charring at the laser catheter-tip in blood during therapeutic laser irradiation by the back scattering light measurement to detect precursor state of the charring. We took account of using photodynamic therapy for arrhythmia in blood through the laser catheter. We observed the influence of the red laser irradiation (λ=663 nm) upon the shape of red blood cells (RBCs). The RBCs aggregation, round formation, and hemolysis were took place sequentially before charring. With a model blood sandwiched between glass plates simulated as a catheter-tip boundary, we measured diffuse-reflected-light power and transmitted-light power simultaneously and continuously by a microscopic optics during the laser irradiation. We found that measured light power changes were originated with RBCs shape change induced by temperature rise due to the laser irradiation. A gentle peak following a slow descending was observed in the diffuse-reflected-light power history. This history might indicate the precursor state of the charring, in which the hemolysis might be considered to advance rapidly. We think that the measurement of diffuse-reflected-light power history might be able to detect precursor state of charring at the catheter-tip in blood. |
| Starting Page | 2759 |
| Ending Page | 2761 |
| File Size | 436918 |
| Page Count | 3 |
| File Format | |
| ISBN | 9781424441235 |
| ISSN | 1557170X |
| DOI | 10.1109/IEMBS.2010.5626585 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-08-31 |
| Publisher Place | Argentina |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Blood Measurement by laser beam Radiation effects Laser modes Temperature measurement History Laser ablation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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