NDLI: An integrated software solution for multi-modal mapping of morphological and functional ocular data

Content Provider	IEEE Xplore Digital Library
Author	Troeger, E. Sliesoraityte, I. Issa, P.C. Scholl, H.P.N. Zrenner, E. Wilke, R.
Copyright Year	2010
Description	Author affiliation: School of Biomedical Engineering, University of New South Wales, Sydney, Australia (Wilke, R.) \|\| Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tuebingen, Germany (Troeger, E.; Sliesoraityte, I.; Zrenner, E.) \|\| Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA (Scholl, H.P.N.) \|\| Nuffield Laboratory of Ophthalmology, University of Oxford, UK (Issa, P.C.)
Abstract	Various morphological and functional techniques for retina examination have been established in the recent years. Although many examination results are spatially resolved and can be mapped onto data originating from other modalities, usually only data from one modality is analyzed by a clinician at a time. This is mainly because there is no software available to the public that enables the registration of structure and function in the clinical setting. Therefore we developed an integrated mapping application that allows the registration and analysis of morphological data (fundus photography, optical coherence tomography, scanning laser ophthalmoscopy images, and GDx thickness profiles) and functional data (multifocal electroretinography, multifocal pattern electroretinography, perimetry, and microperimetry). To obtain quantitative data that can be used for clinical trials and statistical analyses, extraction routines for morphological parameters — such as retinal layer thicknesses and measures of the vascular network — have been integrated. Global, regional and point-specific data from registered modalities can be extracted and exported for statistical analyses. In this article we present the implementation and examples of use of the developed software.
Starting Page	6280
Ending Page	6283
File Size	1740301
Page Count	4
File Format	PDF
ISBN	9781424441235
ISSN	1557170X
DOI	10.1109/IEMBS.2010.5628081
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-08-31
Publisher Place	Argentina
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Retina Image segmentation Software Feature extraction Optical imaging Image registration Optical fibers
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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