NDLI: Effect of L-dopa and Subthalamic Nucleus stimulation on arm and leg swing during gait in Parkinson's Disease

Content Provider	IEEE Xplore Digital Library
Author	Carpinella, I. Crenna, P. Marzegan, A. Rabuffetti, M. Rizzone, M. Lopiano, L. Ferrarin, M.
Copyright Year	2007
Description	Author affiliation: Don Carlo Gnocchi Found. Onlus IRCCS, Milan (Carpinella, I.)
Abstract	The effects of subthalamic nucleus (STN) stimulation and L-dopa administration on the arm and leg swing movements associated with overground walking were studied in a group of patients with idiopathic Parkinson's disease (PD). Ten patients undergoing deep brain stimulation and twenty controls were tested using 3D kinematic motion analysis. Parkinsonian patients under basal conditions walked more slowly and with reduced arm and leg swing compared to controls. Moreover, they displayed significant impairments of the normal interlimb coordination. Both STN stimulation and L-dopa increased the walking speed and the amplitude of arm and leg swing movements. Additional improvements of the coordination between upper and lower limb were documented by reductions of the phase-shift between arm and ipsilateral leg motion, with displacement toward the control range (perfect counterphase). STN stimulation alone and L-dopa alone produced similar effects on the variables analyzed. The combination of the two treatments, instead, yielded additive effects on the gait speed and a slight increase of the upper and lower limb range of motion, in the absence of further improvements in the inter-segmental coordination. Moreover, whereas the increased arm swing could be accounted by the sole adoption of a higher gait speed, both the increment of the leg movement amplitude and the decreased interlimb phase shift appeared to imply an additional effect, possibly related to the treatment. These results may suggest that differential supraspinal controls operate on the neural networks subserving upper and lower limb motion during human walking.
Starting Page	6664
Ending Page	6667
File Size	292951
Page Count	4
File Format	PDF
ISBN	9781424407873
ISSN	1557170X
DOI	10.1109/IEMBS.2007.4353888
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-08-22
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Leg Parkinson's disease Legged locomotion Motion control Brain stimulation Testing Kinematics Motion analysis Displacement control Additives
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Unilateral and Bilateral Subthalamic Nucleus Stimulation in Parkinson's Disease: Effects on EMG Signals of Lower Limb Muscles During Walking

A Model-Based Approach for Assessing Parkinsonian Gait and Effects of Levodopa and Deep Brain Stimulation

An arm for a leg: Adapting a robotic arm for gait rehabilitation

Ambulatory Monitoring of Physical Activities in Patients With Parkinson's Disease

Limb Alignment and Kinematics Inside a Lokomat Robotic Orthosis

Effects of subthalamic nucleus deep brain stimulation and l-dopa on blinking in Parkinson's disease

Measurement of upper limb kinematics and joint angle patterns during deep brain stimulation for parkinson’s disease

Deep brain stimulation for Parkinson's disease prior to L-dopa treatment: A case report

Gait feature extraction in Parkinson's disease using low-cost accelerometers

Effect of L-dopa and Subthalamic Nucleus stimulation on arm and leg swing during gait in Parkinson's Disease

Similar Documents

Unilateral and Bilateral Subthalamic Nucleus Stimulation in Parkinson's Disease: Effects on EMG Signals of Lower Limb Muscles During Walking

A Model-Based Approach for Assessing Parkinsonian Gait and Effects of Levodopa and Deep Brain Stimulation

An arm for a leg: Adapting a robotic arm for gait rehabilitation

Ambulatory Monitoring of Physical Activities in Patients With Parkinson's Disease

Limb Alignment and Kinematics Inside a Lokomat Robotic Orthosis

Effects of subthalamic nucleus deep brain stimulation and l-dopa on blinking in Parkinson's disease

Measurement of upper limb kinematics and joint angle patterns during deep brain stimulation for parkinson’s disease

Deep brain stimulation for Parkinson's disease prior to L-dopa treatment: A case report

Gait feature extraction in Parkinson's disease using low-cost accelerometers

Effect of L-dopa and Subthalamic Nucleus stimulation on arm and leg swing during gait in Parkinson's Disease