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Content Provider | IEEE Xplore Digital Library |
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Author | Yang-Li Yang Ta-Feng Tseng Shyh-Liang Lou |
Copyright Year | 2007 |
Description | Author affiliation: Chung-Yuan Christian Univ., Chung-Li (Yang-Li Yang; Ta-Feng Tseng; Shyh-Liang Lou) |
Abstract | A sol-gel material of (3-mercaptopropyl)trimethoxysilane (MPTMS) is proposed to function as permselective membranes of biosensors. Permselectivity of MPTMS and Nafionreg was compared by studying their anti-interferent ability. Membrane porosity of MPTMS and Nafionreg was first confirmed via voltammetric responses in ferrocynite/ferricynite solution. In the comparison studies, membranes prepared with 20% MPTMS in phosphate buffer solution (PBS) and 1% Nafionreg in 2-propanol (IPA) were used as coating materials on the surface of two platinum (Pt) electrodes. These electrodes were used to electrochemically measure the response currents of ascorbic acid, uric acid, and acetaminophen. The results indicate that the MPTMS-based electrode produced much less response currents from the interference species compared to that of the Nafionreg-based electrode. This denotes that the anti-interferent ability of MPTMS is superior to that of Nafionreg. A platinum working electrode containing glucose oxidase (GOx) immobilized by poly-aniline (PA) and then modified by MPTMS was developed and evaluated. The results show that the optimum applied potential for the glucose biosensor is 0.4 V. This operational potential not only inhibits the response currents from ascorbic acid, uric acid, and acetaminophen but also produces rather high signals for glucose. |
Starting Page | 6624 |
Ending Page | 6627 |
File Size | 624610 |
Page Count | 4 |
File Format | |
ISBN | 9781424407873 |
ISSN | 1557170X |
DOI | 10.1109/IEMBS.2007.4353878 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2007-08-22 |
Publisher Place | France |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Biomembranes Biosensors Sugar Electrodes Biological materials Platinum Biomedical measurements Current measurement Interference Conducting materials |
Content Type | Text |
Resource Type | Article |
Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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