NDLI: An Integrated Biosensor for the Detection of Bio-entities Using Magnetotactic Bacteria and CMOS Technology

Content Provider	IEEE Xplore Digital Library
Author	El Fouladi, J. Zhao Lu Savaria, Y. Martel, S.
Copyright Year	2007
Description	Author affiliation: Ecole Polytech. de Montreal, Montreal (El Fouladi, J.; Zhao Lu; Savaria, Y.; Martel, S.)
Abstract	An integrated biosensor for the detection of micron-size biological entities using magnetotactic bacteria (MTB) being guided under the control of an external magnetic field of a few Gauss is briefly described. The proposed biosensor will be implemented onto a silicon substrate compatible with standard CMOS technologies. To validate the proposed concept, a microfluidic device and a microelectronic chip have been fabricated. Pairs of planar microelectrodes are patterned on the bottom of a microchannel and connected with the microelectronic chip. When a microbead pushed by a single MTB passes between a pair of microelectrodes, a variation in electrical impedance is measured by embedded detection circuits. The paper reviews the proposed microsystem. It emphasizes the sensing principle and describes the technique for implementing the microelectrodes. Finally, the paper reports preliminary experimental results obtained with an integrated circuit implementing the interfacing electronics that confirm the feasibility of turning distinct impedance levels into digital decisions that would reflect the presence of biological entities, especially bacteria or functional microbeads.
Starting Page	119
Ending Page	122
File Size	692162
Page Count	4
File Format	PDF
ISBN	9781424407873
ISSN	1557170X
DOI	10.1109/IEMBS.2007.4352237
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-08-22
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	CMOS technology Biosensors Microorganisms Microelectrodes Microelectronics Impedance Biological control systems Magnetic fields Gaussian processes Silicon
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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