NDLI: Computer based modeling of the congenital long-QT 2 syndrome in the Visible Man torso: From genes to ECG

Content Provider	IEEE Xplore Digital Library
Author	Keller, D.U.J. Seemann, G. Weiss, D.L. Farina, D. Zehelein, J. Dossel, O.
Copyright Year	2007
Description	Author affiliation: Univ. Karlsruhe, Karlsruhe (Keller, D.U.J.; Seemann, G.; Weiss, D.L.; Farina, D.)
Abstract	The congenital long-QT syndrome is commonly associated with a high risk for polymorphic ventricular tachycardia and sudden cardiac death. This is probably due to an intensification of the intrinsic heterogeneities present in ventricular myocardium. Increasing the electrophysiological heterogeneities amplifies the dispersion of repolarization which directly affects the morphology of the T wave in the ECG. The aim of this work is to investigate the effects of LQT2, a specific subtype of the long-QT syndrome (LQTS), on the Body Surface Potential Maps (BSPM) and the ECG. In this context a three-dimensional, heterogeneous model of the human ventricles is used to simulate both physiological and pathological excitation propagation. The results are used as input for the forward calculation of the BSPM and ECG. Characteristic QT prolongation is simulated correctly. The main goal of this study is to prepare and evaluate a simulation environment that can be used prospectively to find features in the ECG or the BSPM that are characteristic for the LQTS. Such features might be used to facilitate the identification of LQTS patients.
Starting Page	1410
Ending Page	1413
File Size	981181
Page Count	4
File Format	PDF
ISBN	9781424407873
ISSN	1557170X
DOI	10.1109/IEMBS.2007.4352563
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-08-22
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Torso Electrocardiography Biological system modeling Humans Heart Solid modeling Myocardium Surface morphology Context modeling Genetics
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Predicting the optimal position and direction of a ubiquitous ECG using a multi-scale model of cardiac electrophysiology

Accuracy of QT Measurement in the EASI-derived 12-lead ECG

Numerical simulation of motion-induced dynamic noise in a ubiquitous ECG application

Noncontact ECG system for unobtrusive long-term monitoring

Modeling the different sections of the cardiac conduction system to obtain realistic electrocardiograms

Effect of using ECG derived respiration (EDR) signal in linear parametric QT-RR modeling

Variability of action potential duration in pharmacologically induced long QT syndrome type 1

Conduction abnormalities in the right ventricular outflow tract in Brugada syndrome detected body surface potential mapping

Using tele-medical electrocardiography monitoring and analysis for a more immediate prognosis to patients of suspect Long QT Syndrome

Computer based modeling of the congenital long-QT 2 syndrome in the Visible Man torso: From genes to ECG

Similar Documents

Predicting the optimal position and direction of a ubiquitous ECG using a multi-scale model of cardiac electrophysiology

Accuracy of QT Measurement in the EASI-derived 12-lead ECG

Numerical simulation of motion-induced dynamic noise in a ubiquitous ECG application

Noncontact ECG system for unobtrusive long-term monitoring

Modeling the different sections of the cardiac conduction system to obtain realistic electrocardiograms

Effect of using ECG derived respiration (EDR) signal in linear parametric QT-RR modeling

Variability of action potential duration in pharmacologically induced long QT syndrome type 1

Conduction abnormalities in the right ventricular outflow tract in Brugada syndrome detected body surface potential mapping

Using tele-medical electrocardiography monitoring and analysis for a more immediate prognosis to patients of suspect Long QT Syndrome

Computer based modeling of the congenital long-QT 2 syndrome in the Visible Man torso: From genes to ECG