NDLI: Optimal Dual Time Point for FDG-PET in the Differentiation of Benign from Malignant Lung Lesions: A Simulation Study

Content Provider	IEEE Xplore Digital Library
Author	Rui Jia Eberl, S. Lingfeng Wen Jing Bai Feng, D.D.
Copyright Year	2007
Description	Author affiliation: Tsinghua Univ., Beijing (Rui Jia; Jing Bai) \|\| Univ. of Sydney, Sydney (Eberl, S.; Lingfeng Wen; Feng, D.D.)
Abstract	Dual time point imaging has been proposed as a means of improving the accuracy of Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in the diagnosis of lung malignancy. However, various sampling schedules have been used, which makes direct comparisons between their results difficult. It is unclear whether these schedules have the same accuracy for the diagnosis of lung malignancy, limiting the further development and adoption of these techniques. Although theoretically malignant and benign lesions show increasing difference in FDG uptake with longer uptake periods, the increasing noise due to decay may counteract this advantage and increase variability. In this paper, a method for the design of an optimal dual time point 18F-FDG PET imaging protocol has been proposed to address this issue.
Starting Page	4169
Ending Page	4172
File Size	266480
Page Count	4
File Format	PDF
ISBN	9781424407873
ISSN	1557170X
DOI	10.1109/IEMBS.2007.4353255
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-08-22
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cancer Lungs Lesions Positron emission tomography Protocols Sampling methods Biomedical engineering Kinetic theory Neoplasms Australia
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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