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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Dehkhoda, F. Soltan, A. Ramezani, R. Zhao, H. Liu, Y. Constandinou, T. Degenaar, P. |
| Copyright Year | 2015 |
| Description | Author affiliation: Sch. of Electr. & Electron. Eng., Newcastle Univ., Newcastle upon Tyne, UK (Dehkhoda, F.; Soltan, A.; Ramezani, R.; Zhao, H.; Degenaar, P.) || Imperial Coll. London, London, UK (Liu, Y.; Constandinou, T.) |
| Abstract | Implantable neuro-prosthetics have provided considerable clinical benefit to a range of neurological conditions. Optogenetics is a particular recent interest which utilizes high radiance light for photo-activation of genetically altered nerve cells. This can provide improved biocompatibility and neural targeting over electrical stimuli. To date the primary optical delivery method in tissue for optogenetics has been via optic fibre which makes large scale multiplexing difficult. An alternative approach is to incorporate optical micro-emitters directly on implantable probes but this still requires electrical multiplexing. In this work, we demonstrate a fully active optoelectronic probe utilizing industry standard 0.35μm CMOS technology, capable of both light delivery and electrical recording. The incorporation of electronic circuits onto the device further allows us to incorporate smart sensors to determine diagnostic state to explore long term viability during chronic implantation. |
| Sponsorship | IEEE |
| Starting Page | 1 |
| Ending Page | 4 |
| File Size | 1571336 |
| Page Count | 4 |
| File Format | |
| e-ISBN | 9781479982035 |
| DOI | 10.1109/ICSENS.2015.7370687 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2015-11-01 |
| Publisher Place | South Korea |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Light emitting diodes Shafts Biomedical optical imaging Optical sensors Stimulated emission CMOS integrated circuits Optical fibers biophotonics optogenetics optrode micro-LED temperature sensor biomedical implant |
| Content Type | Text |
| Resource Type | Article |
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