NDLI: An implantable 64-channel neural interface with reconfigurable recording and stimulation

Content Provider	IEEE Xplore Digital Library
Author	Wheeler, J.J. Baldwin, K. Kindle, A. Guyon, D. Nugent, B. Segura, C. Rodriguez, J. Czarnecki, A. Dispirito, H.J. Lachapelle, J. Parks, P.D. Moran, J. Widge, A.S. Dougherty, D.D. Eskandar, E.N.
Copyright Year	2015
Description	Author affiliation: Dept. of Psychiatry, Massachusetts Gen. Hosp. & Harvard Med. Sch., Boston, MA, USA (Widge, A.S.; Dougherty, D.D.) \|\| Dept. of Neurological Surg., Med. Sch., Harvard Univ., Boston, MA, USA (Eskandar, E.N.) \|\| Charles Stark Draper Lab., Cambridge, MA, USA (Wheeler, J.J.; Baldwin, K.; Kindle, A.; Guyon, D.; Nugent, B.; Segura, C.; Rodriguez, J.; Czarnecki, A.; Dispirito, H.J.; Lachapelle, J.; Parks, P.D.; Moran, J.)
Abstract	Next generation implantable medical devices will have the potential to provide more precise and effective therapies through adaptive closed-loop controllers that combine sensing and stimulation across larger numbers of electrode channels. A major challenge in the design of such devices is balancing increased functionality and channel counts with the miniaturization required for implantation within small anatomical spaces. Customized therapies will require adaptive systems capable of tuning which channels are sensed and stimulated to overcome variability in patient-specific needs, surgical placement of electrodes, and chronic physiological responses. In order to address these challenges, we have designed a miniaturized implantable fully-reconfigurable front-end system that is integrated into the distal end of an 8-wire lead, enabling up to 64 electrodes to be dynamically configured for sensing and stimulation. Full reconfigurability is enabled by two custom 32×2 cross-point switch (CPS) matrix ASICs which can route any electrode to either an amplifier with reprogrammable bandwidth and integrated ADC or to one of two independent stimulation channels that can be driven through the lead. The 8-wire circuit includes a digital interface for robust communication as well as a charge-balanced powering scheme for enhanced safety. The system is encased in a hermetic package designed to fit within a 14 mm bur-hole in the skull for neuromodulation of the brain, but could easily be adapted to enhance therapies across a broad spectrum of applications.
Starting Page	7837
Ending Page	7840
File Size	942894
Page Count	4
File Format	PDF
ISSN	1557170X
e-ISBN	9781424492718
DOI	10.1109/EMBC.2015.7320208
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-08-25
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrodes Satellites Application specific integrated circuits Switches Electric potential Medical treatment Phantoms Neural interfaces - Microsystems and microfabrication Neural stimulation - Deep brain Neural interfaces - Implantable systems
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Package architecture and component design for an implanted neural stimulator with closed loop control

A wireless 64-channel ECoG recording Electronic for implantable monitoring and BCI applications: WIMAGINE

Multichannel neural recording with a 128 Mbps UWB wireless transmitter for implantable brain-machine interfaces

Neural Recording Front-End Designs for Fully Implantable Neuroscience Applications and Neural Prosthetic Microsystems

Recent Advances in Neural Recording Microsystems

A bidirectional 64-channel neurochip for recording and stimulation neural network activity

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

An Implantable 64-Channel Wireless Microsystem for Single-Unit Neural Recording

256-channel reconfigurable system for recording the electrophysiological activity of a neural tissue in vitro

An implantable 64-channel neural interface with reconfigurable recording and stimulation

Similar Documents

Package architecture and component design for an implanted neural stimulator with closed loop control

A wireless 64-channel ECoG recording Electronic for implantable monitoring and BCI applications: WIMAGINE

Multichannel neural recording with a 128 Mbps UWB wireless transmitter for implantable brain-machine interfaces

Neural Recording Front-End Designs for Fully Implantable Neuroscience Applications and Neural Prosthetic Microsystems

Recent Advances in Neural Recording Microsystems

A bidirectional 64-channel neurochip for recording and stimulation neural network activity

Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

An Implantable 64-Channel Wireless Microsystem for Single-Unit Neural Recording

256-channel reconfigurable system for recording the electrophysiological activity of a neural tissue in vitro

An implantable 64-channel neural interface with reconfigurable recording and stimulation